BRD Antimicrobial Comparison Chart

To find the most effective solution for your operation, explore the BRD Solutions portfolio, including Draxxin® KP, Draxxin®, Excede® and Advocin®.

Product
Associated with:
Mannheimia haemolytica
Associated with:
Pasteurella multocida
Associated with:
Histophilus somni
Associated with:
Mycoplasma bovis
Dosage
(per cwt)
Estimated Duration
Meat Withdrawal
(days)
 
Control
Treat
Control
Treat
Control
Treat
Control
Treat
     
(tulathromycin and ketoprofen Injection)
No Yes No Yes No Yes No Yes 1.1 mL 14 days 1 18
(tulathromycin injection)
Yes Yes Yes Yes Yes Yes Yes Yes 1.1 mL 14 days 2 18
(ceftiofur crystalline free acid)
Yes Yes Yes Yes Yes Yes No No 1.5 ml 7 days 3 13
(danofloxacin injection)
Yes Yes Yes Yes No No No No 1.5–2 mL ** 4
Other Products
Baytril®
(enrofloxacin)
Yes Yes Yes Yes Yes Yes Yes Yes 3.4–5.7 mL ** 28
Micotil®
(tilmicosin)
Yes Yes No Yes No Yes No No 1.5–3 mL ** 42
Nuflor®
(florfenicol)
Yes Yes Yes Yes Yes Yes No No 3–6 mL **
38 (SC)
28 (IM)
Resflor Gold®
(florfenicol adn flunixin meglumine)
No Yes No Yes No Yes No Yes 6 mL N/A
38
Zactran®
(gamithromycin)
Yes Yes Yes Yes No Yes No Yes 1.82 mL 10 days 4,5 35
Zuprevo®
(tildipirosin)
Yes Yes Yes Yes Yes Yes No No 1 mL ** 21
Safety Information

IMPORTANT SAFETY INFORMATION FOR DRAXXIN KP: Draxxin KP has a pre-slaughter withdrawal time of 18 days in cattle. Not for use in female dairy cattle 1 year of age or older, including dry dairy cows. Not for use in beef calves less than 2 months of age, dairy calves, and veal calves. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in animals previously found to be hypersensitive to tulathromycin and ketoprofen. See full Prescribing Information

IMPORTANT SAFETY INFORMATION FOR DRAXXIN: Draxxin has a pre-slaughter withdrawal time of 18 days. Do not use in female dairy cattle 20 months of age or older. Do not use in animals known to be hypersensitive to the product. Full Prescribing Information

IMPORTANT SAFETY INFORMATION FOR EXCEDE: People with known hypersensitivity to penicillin or cephalosporins should avoid exposure to Excede. Excede is contraindicated in animals with known allergy to ceftiofur or to the ß-lactam group (penicillins and cephalosporins) of antimicrobials. Inadvertent intra-arterial injection is possible and fatal. Do not use in calves to be processed for veal. Pre-slaughter withdrawal time is 13 days following the last dose. Full Prescribing Information

IMPORTANT SAFETY INFORMATION FOR ADVOCIN: Extra-label use of Advocin in food-producing animals is prohibited. Do not use in cattle intended for dairy production or in calves to be processed for veal. Advocin has a pre-slaughter withdrawal time of four days. Full Prescribing Information

Baytril is a registered trademark of Bayer Aktiengesellschaft. Micotil is a registered trademark of Elanco US Inc. Nuflor, Resflor Gold and Zuprevo are registered trademarks of Intervet Inc. or an affiliate. Zactran is a registered trademark of Boehringer Ingelheim Animal Health.

  1. Data on file, Study Report No. A431N-US-16-418, Zoetis Inc. 
  2. Freedom of Information Summary. NADA 141-244 — Draxxin® (tulathromycin injection) Injectable Solution. Food and Drug Administration; 2005. 
  3. Data on file, Study Report No. 1133R-60-05-489, Zoetis Inc. 
  4. Lechtenberg K, Daniels CS, Royer GC, et al. Field Efficacy Study of Gamithromycin for the Control of Bovine Respiratory Disease in Cattle at High Risk of Developing the Disease. Intern J Appl Res Vet Med. 2011;9(2):189-197. 
  5. Sifferman RL, Wolff WA, Holste JE, et al. Field Efficacy Evaluation of Gamithromycin for Treatment of Bovine Respiratory Disease in Cattle at Feedlots. Intern J Appl Res Vet Med. 2011;9(2):166-175.