What's the Impact of Your First Treatment Choice?

Your first choice to help treat bovine respiratory disease (BRD) makes a bigger impact than you might think.

There are two schools of thought when you’re dealing with BRD treatment. Do you:

  1. Treat with a less expensive, less effective antimicrobial first and save a more effective product as a last resort?
  2. Start with the most effective antimicrobial first to help treat BRD?

In a recent meta-analysis published in the Bovine Practitioner journal, of 31 trials evaluated, Zoetis found that using DRAXXIN® (tulathromycin) Injectable Solution as the first choice for control or treatment of BRD resulted in fewer treatment courses than seven other injectable products. In fact, choosing DRAXXIN as the initial BRD treatment, rather than other antimicrobials, could help producers avoid up to 1.8 million treatments each year in the U.S.1

U.S. beef producers could avoid up to 1.8 million treatments annually using DRAXXIN® for BRD treatment and control.Just how big of an impact can reduced treatments make? Choosing a more effective option the first time for BRD treatment may contribute to more than just BRD treatment success. Choosing the right antimicrobial to treat and control BRD can positively impact:


Healthier animals are happier animals, and these cattle can perform better. Making fewer BRD treatments reduces cattle stress from reduced pulls and re-treats and lessens the chance for long-term health impacts and performance loss. Don’t overlook that you’re also reducing your BRD mortality rate by 50% with DRAXXIN compared with competitive antimicrobials. That’s a lot more healthy cattle.1,2


Fewer treatments means improved labor efficiencies, reducing time spent pulling and re-treating cattle for your cowboys, who are already putting in a full day’s hard work.


Selecting the most effective antimicrobial for the first BRD treatment choice decreases re-treats and overall treatment costs — keeping more dollars in producers’ pockets and contributing to an improved bottom line. 

The Beef Industry

Fewer re-treats also represent a reduced total number of antibiotic treatments across the cattle industry.


With the majority of injectable feedlot antimicrobials for treatment of BRD classified by the World Health Organization as belonging to the group of antimicrobials critically important to human medicine, it’s vital that these valuable resources remain effective. Working with a veterinarian to use the most effective antibiotic, or right antibiotic at the right time, ensures these products are used in ways that protect both animal and human health while meeting the strict food safety standards of government oversight agencies. This means:

  • More responsible use of antibiotics
  • Fewer risks for residue violations
  • Reduced chance for antibiotic resistance

A simple decision, like the first-choice antimicrobial to treat BRD, can help make a bigger impact than one might think. It not only impacts the success of a BRD treatment plan but also the industry and overall cattle health and well-being.

IMPORTANT SAFETY INFORMATION: DRAXXIN has a pre-slaughter withdrawal time of 18 days in cattle. Do not use in female dairy cattle 20 months of age or older. Do not use in animals known to be hypersensitive to the product. Full Prescribing Information.

*Estimates based on the use of DRAXXIN as a first-line choice for control or treatment of BRD per year in the U.S.1

Poulsen Nautrup B, Van Vlaenderen I, Decker M, Cleale RM. Antimicrobial drug use for control and treatment of bovine respiratory disease in U.S. feedlot cattle: A meta-analysis. Bov Pract.2017;51(1);1-13.*
2 O’Connor AM, Coetzee JF, da Silva N and Wang C. A mixed treatment comparison meta-analysis of antibiotic treatments for bovine respiratory disease. Prev Vet Med. 2013;110(2):77-87.

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